Aztreonam

Zetraβan 1000 mg — Aztreonam Injection USP

Zetraβan is a high-potency Aztreonam injection (1000 mg) designed for intravenous (IV) or intramuscular (IM) administration to treat serious Gram-negative bacterial infections.

🌐 Key Features

• Broad-spectrum Gram-negative coverage: Effective against E. coli, Klebsiella, Proteus, Pseudomonas aeruginosa, and other aerobic Gram-negative bacilli.

• Bactericidal action: Inhibits bacterial cell wall synthesis via penicillin-binding protein‑3 (PBP‑3), leading to bacterial death.

• Low cross-allergenicity: Safe option for many patients allergic to penicillin or cephalosporins.

• Single-use vial: 1000 mg per vial for precise dosing; ready for IV or IM administration.

⚠️ Usage & Safety

• Route: IV or IM only — not for oral use.

• Indications: Serious infections including urinary tract infections, pneumonia, septicemia, abdominal infections, and skin/soft tissue infections caused by susceptible Gram-negative bacteria.

• Precautions: Use under medical supervision. Monitor for allergic reactions, kidney function, and complete the full course.

❓ FAQs (Up to 8)

1. What is Zetraβan used for?
   Treats serious Gram-negative bacterial infections like urinary tract infections, pneumonia, septicemia, and abdominal infections.

2. How does Aztreonam work?
   It disrupts bacterial cell wall synthesis by binding to penicillin-binding protein‑3 (PBP‑3), causing bacterial death.

3. Can Zetraβan be taken orally?
   No. It is only effective via IV or IM injection.

4. Is it safe for patients allergic to penicillin?
   Generally yes; it has low cross-reactivity with penicillin and cephalosporin allergies.

5. What bacteria is it effective against?
   Effective against aerobic Gram-negative bacteria like E. coli, Klebsiella, Proteus, Pseudomonas aeruginosa, and Haemophilus influenzae.

6. What is the recommended dose?
   Administer under a doctor’s guidance. Single-use vial contains 1000 mg for IV or IM injection.

7. Are there any side effects?
   Common: injection site reactions, rash, nausea, vomiting. Rare: allergic reaction, kidney or liver issues.

8. Can it replace oral antibiotics?
   No. It’s for serious infections requiring IV/IM therapy under medical supervision.

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