Meropenem & Sulbactam

Meropenem & Sulbactam Injection 1.5 gm (Meroban-S) is a broad-spectrum intravenous antibiotic combining meropenem, a carbapenem antibiotic, and sulbactam, a beta-lactamase inhibitor. This combination enhances bacterial coverage and is effective against resistant strains causing serious infections.

It is administered via IV infusion after reconstitution, offering rapid therapeutic levels in hospitalized patients.

Key Features & Benefits

• Active Ingredients: Meropenem + Sulbactam

• Route: Intravenous (IV) injection

• Broad-spectrum: Effective against Gram-positive, Gram-negative, and resistant bacteria

• Rapid Action: Quickly achieves therapeutic concentration in blood

• Enhanced Efficacy: Sulbactam inhibits beta-lactamase enzymes, improving antibiotic performance

• High Purity: Manufactured under strict quality standards

Indications

Meroban-S Injection is indicated for:

• Severe respiratory tract infections (pneumonia, bronchitis)

• Urinary tract infections (UTIs)

• Intra-abdominal infections

• Skin and soft tissue infections

• Septicemia and bloodstream infections

• Bone and joint infections

Dosage & Administration

• Reconstitution: Powder must be dissolved in sterile water or compatible IV diluent before infusion.

• Infusion: Administered slowly over 30–60 minutes depending on the severity.

• Typical Adult Dose: 1.5 gm IV every 8 hours (adjusted for kidney function).

• Pediatric Dose: Dose based on body weight and clinical condition.

• Professional Supervision: Must be administered by trained healthcare personnel.

(Exact doses should always be determined by a physician.)

Precautions & Safety

• Only for intravenous use; do not administer intramuscularly.

• Use caution in patients with renal impairment.

• Monitor for allergic reactions, especially in patients with penicillin or cephalosporin allergy.

• Infusion site reactions may occur; rotate sites when possible.

• Store at controlled room temperature, protected from light.

Side Effects

Common side effects may include:

• Nausea and vomiting

• Diarrhea

• Headache

• Rash or mild allergic reactions

Serious reactions (rare) may include:

• Severe allergic reaction (anaphylaxis)

• Seizures in patients with CNS disorders

• Clostridium difficile-associated diarrhea

Frequently Asked Questions (FAQs)

1. What is Meroban-S Injection used for?
It is used to treat serious bacterial infections including respiratory, urinary, intra-abdominal, and bloodstream infections.

2. How is it administered?
Administered intravenously after reconstitution by trained healthcare professionals.

3. Can it be self-administered?
No — it requires professional medical supervision due to risk of adverse reactions.

4. What is the usual adult dose?
Typically 1.5 gm IV every 8 hours, adjusted according to kidney function and severity.

5. Are there side effects?
Common effects: nausea, diarrhea, headache, mild rash. Serious effects are rare but possible.

6. Can it be used in children?
Yes — pediatric doses are calculated based on body weight and clinical condition.

7. Are there precautions during treatment?
Yes — monitor for allergic reactions, infusion site reactions, and adjust dose for renal impairment.

8. How should it be stored?
Store at room temperature, away from direct sunlight, and use within recommended time after reconstitution.

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